Prevalence of Diabetes Mellitus II and Impaired Fasting Glycemia in Patients Diagnosed with Pulmonary Tuberculosis at the Bamenda Regional Hospital - Cameroon

Authors

  • Mary Chia- Garba Faculty of Health Sciences, Department of Medical Laboratory Sciences, University of Bamenda, Cameroon.
  • Asanghanwa Milca Faculty of Health Sciences, Department of Medical Laboratory Sciences, University of Bamenda, Cameroon.
  • Agbor Esther Etengeneng Faculty of Health Sciences, Department of Medical Laboratory Sciences, University of Bamenda, Cameroon.
  • Lidi Lorretta A Faculty of Health Sciences, Department of Medical Laboratory Sciences, University of Bamenda, Cameroon.

Keywords:

Diabetes Mellitus, Impaired Fasting Glycemia, Pulmonary Tuberculosis, Bamenda Regional hospital – Cameroon

Abstract

The rising prevalence of diabetes mellitus (DM) and its association with tuberculosis (TB) and the persistence is a major public health problem worldwide, especially in developing countries,thus emphasizing the importance of investigating this association. This study was aimed at investigating the prevalence of Diabetes mellitus II and impaired fasting glycaemia in patients diagnosed with pulmonary TB at the Bamenda Regional Hospital .An experimental and prospective design, involving 91 patients diagnosed of pulmonary TB and 68 sputum negative patients were used as control. Venous blood was collected from each participant and was analyzed using the CHRONO LAB system chemistry analyzer to screen for impaired fasting glycaemia and Diabetes mellitus. Information to assess the knowledge and perception of both TB and DM of the participants was gotten through questionnaires. This study revealed that the total prevalence of diabetes mellitus was 29.7% while that of IFG was 16.5% amongst TB patients receiving care at the Bamenda Regional hospital compared to the 26.6% DM and 2.9% IFG for the control group. In total, 42(46.2%) of the test population were hyperglycemic (IFG/DM) compared to 16(23.5%) of the control group and this difference was statistically significant (p<0.05)  More males (28%) in this study were hyperglycemic than females ( 21%) but the difference was statistically not sgnificant,   26% of alcohol consumers were more hyperglycemic than non alcohol consumers and the difference was statistically significant ( p< 0.05). The age range of 31 – 40 years had the highest prevalence level ( 9%) of  DM  and 7% of IFG and those below 20 years had the lowest glycemic levels. Findings from this study revealed that TB patients had a higher prevalence of DM and IFG compared to the control population (sputum negative patients).The screening of diabetes in patients with pulmonary tuberculosis is recommended for successful treatment, control and patient care of the two diseases.

References

. .Jean-Claude Manya and Kaushik Ramiaya. Disease and Mortality in Sub-Saharan Africa 2nd Edition

. IND. J. Tab. Tuberculosis and Diabetes. Leading article 2000. 47, 3- pg 1-6

. infectious diseases Advanced Access. August 10, 2016 pg 1-49

. Syed A Zhar Syed, Pharm D, Amer Hayat Khan, PHD, Abdul Razak, Muttalif, MBBS, Mohamed azmiHassali, Phd, Nafees Ahmad, Msc and Muhammad ShahidIqubal, Phd. Impact of DM on treatment outcomes of TB patients in 3rd degree care setup. The American journal of medical Sciences. Volume 345, number 4, April 2013. Pg 1-5

. Dooley KE, Chaisson RE. TB and DM: convergence of two epidermics the lancet infectious Diseases. 2009; 9(12): 737- 46

. McMillin JM, Blood Glucose-clinical methods, 1990.

. World Health Organisation. Diabetes mellitus report: Report of a WHO Study Group in Geneve. Technical Report. 1985;727

. Jeon CY, Harries AD, Baker MA, et al. Bi-directional screening for tuberculosis and diabetes: a systematic review. Tropical Medicine & International Health 2010; 15: 1300-14.

. Balakrishnan S, Vijayan S, Nair S, Subramoniapillai J, Mrithyunjayan S, Wilson N, et al. High diabetes prevalence among tuberculosis cases in Kerala, India. PLoS One 2012;7: e46502. .

. Leung CC, Lam TH, Chan WM, et al. Diabetic control and risk of tuberculosis: a cohort study. Am J Epidemiol.2008; 167:1486–94.

. SohilMansuri, AshishChaudhari, Anoop Singh, RahimaMalek, RinkalViradiya. Prevalence of Diabetes among Tuberculosis Patients at Urban Health Centre, Ahmedabad. International Journal of Scientific Study | July 2015 | Vol 3 | Issue 4

. Nijland HMJ, Ruslami R, Stalenhoef JE, Nelwan EJ, Alisjahbana B, Nelwan RHH. et al. Exposure to rifampicin is strongly reduced in patients with tuberculosis and type 2 diabetes. Clin Infect Dis. 2006;43(7):848–854. doi: 10.1086/507543.

. Raviglione MC, Sudre P, Riedei HL, Spinaci S, Koch A. Secular trends of tuberculosis in Western Europe: Epidemiological situation in 14 countries. World Health Organization, 1992.

. Corbett, Watt CJ, Walker N, Maher D, Williams BG, MC, Dye C: The growing burden of tuberculosis: global trends and interactions with the HIV epidemic. Arch Intern Med 2003; 163:1009- 21.

. Silveira JM, Sassi RAM, Oliveira Netto ICD, Hetzel JL. Prevalence of and factors related to tuberculosis in seropositive human immunodeficiency virus patients at a reference center for treatment of human immunodeficiency virus in the southern region of the state of Rio Grande do Sul, Brazil. J Bras Pneumol. 2006;32(1):48-55.

. Raviglione MC, Sudre P, Riedei HL, Spinaci S, Koch A. Secular trends of tuberculosis in Western Europe: Epidemiological situation in 14 countries. World Health Organization, 1992.

. Corbett EL, Watt CJ, Walker N, Maher D, Williams BG, Raviglone MC, Dye C: The growing burden of tuberculosis: global trends and interactions with the HIV epidemic. Arch Intern Med 2003; 163:1009- 21.

. P. Alfredo, G. Lourdes, S. Cecilia et al., “Tuberculosis and diabetes in Southern Mexico,” Diabetes Care, vol. 27, no. 7, pp. 1584–1590, 2004. View at: Publisher Site | Google Scholar

. Kirigia JM, Sambo HB, Sambo LG, Barry SP. Economic burden of diabetes mellitus in the WHO African region. BMC Int Health Hum Rights. 2009;9:6.

. Pan SC, Ku C, Kao , Ezzati M, Fang CT, Lin HH. Effect of diabetes on tuberculosis control in 13 countries with high tuberculosis: a modelling study. Lancet Diabetes Endocrinol. 2015;3:323–330 pmid:25754415.

. Reid MJ, Oyewo A, Molosiwa B, McFadden N, Tsima B, Ho-Foster A. Screening for tuberculosis in a diabetes clinic in Gaborone, Botswana. Int J Tuberc Lung Dis. 2014;18(8):1004. pmid:25199021.

. Adepoyibi T, Weigl B, Greb H, Neogi T, McGuire H. New screening technologies for type 2 diabetes mellitus appropriate for use in tuberculosis patients. Public Health Action 2013; 3 Suppl 1: S10– S17. pmid:26393062.

. Whitley HP, Yong EV, Rasinen C. Selecting an A1C Point-of-Care Instrument. Diabetes Spectr. 2015; 28(3):201–8. pmid:26300614.

. WHO. Global Tuberculosis Report 2017. Geneva 2017.

. G. Assefa, M. Solomon, A. Shiatye, and Y. Hanan, “High magnitude of diabetes mellitus among active pulmonary tuberculosis patients in Ethiopia,” British Journal of Medicine & Medical Research, vol. 4, no. 3, pp. 862–872, 2013. View at: Publisher Site | Google Scholar

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Published

2021-03-21

How to Cite

Chia- Garba, M. ., Milca, A. ., Etengeneng , A. E. ., & Lidi Lorretta A. (2021). Prevalence of Diabetes Mellitus II and Impaired Fasting Glycemia in Patients Diagnosed with Pulmonary Tuberculosis at the Bamenda Regional Hospital - Cameroon. American Scientific Research Journal for Engineering, Technology, and Sciences, 78(1), 9–21. Retrieved from https://asrjetsjournal.org/index.php/American_Scientific_Journal/article/view/6645

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