Identification and Characterization of the Antibacterial Activity of Fungal Metabolites on Contaminants Responsible for Foodborne Diseases

  • Menonve Atindehou Unité de Biochimie et de Biologie Moléculaire / Université d’Abomey-Calavi, 04BP0320, Cotonou, Bénin
  • Yann Christie S. Adjovi Ecole des Sciences et Techniques de Conservation et de Transformation des Produits Agricoles / Université Nationale d’Agriculture, BP 114 Sakété, Bénin, Unité de Biochimie et de Biologie Moléculaire / Université d’Abomey-Calavi, 04BP0320, Cotonou, Bénin
  • Gilchrist M. G. Dagbozounkou Unité de Biochimie et de Biologie Moléculaire / Université d’Abomey-Calavi, 04BP0320, Cotonou, Bénin
  • Lucie Ayi Fanou Unité de Biochimie et de Biologie Moléculaire / Université d’Abomey-Calavi, 04BP0320, Cotonou, Bénin
Keywords: Bacterial resistance, Synergistic effect, Nigrospora, Aspergillus, Penicillium

Abstract

The emergence of new diseases due to recurrent food poisoning nowadays in the face of excessive use of conventional antibiotics leads to the search for new bioactive molecules. Thus, the objective of this work was to investigate the antibacterial activity of fungal metabolites on contaminants responsible for food poisoning. To do this, Eight (08) fungal strains belonging to the genera Aspergillus, Penicillium and Nigrospora were used and antibacterial tests were performed on 4 bacterial strains (Staphylococcus aureus ATCC 25923, Shigella sp, Escherichia coli sp and Salmonella sp) using the agar cylinder method (antibiotic). The results showed that seven (07) fungal isolates have high antibacterial activity with inhibition diameters ranging from 18 to 29 mm on Staphylococcus Aureus ATCC 25923; Shigella sp; Salmonella sp and Escherichia coli. Synergistic tests have shown that the combination of 4 to 5 fungal strains could increase bacterial inhibition of Staphylococcus, Salmonella, Shigella and Escherichia coli which appear resistant to the action of a single fungal strain.

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Published
2020-02-04
Section
Articles