Determination Sunscreen Potential Based on Sunflower Seed Oil (Helianthus Annuus) in Cream Preparation With Combination of Oxybenzone and Octyl Methoxycinnamate by in Vitro Method

  • Novi Tamara Master of Biomedical Science, Faculty of Medicine, Prima Indonesia University, Medan, North Sumatera, Indonesia
  • Celvin Angkasa Master of Biomedical Science, Faculty of Medicine, Prima Indonesia University, Medan, North Sumatera, Indonesia
  • Chrismis Novalinda Ginting Faculty of Medicine, Prima Indonesia University, Medan, North Sumatera, Indonesia
  • Linda Chiuman Faculty of Medicine, Prima Indonesia University, Medan, North Sumatera, Indonesia
  • I Nyoman Ehrich Lister Department of Physiology, Faculty of Medicine, Prima Indonesia University, Medan, North Sumatera, Indonesia
Keywords: Sun Exposure, Sunscreen, Sunflower Seed Oil, Oxybenzone, Octyl Methoxycinnamate, SPF, pH, spectrophotometer UV-Vis

Abstract

Sun exposure can cause erythema and sunburn to cause degeneration of the skin such as premature aging and some skin cancers. Due to the negative effects of the sun's rays, we need to use a sunscreen skin protector. Natural materials for sunscreen preparations is commonly use because it is easy accept by the community. Sunflower seed oil is one of the natural ingredients that contains vitamin E which is as an antioxidant and also has the potential as a sunscreen. This study is purpose to determine the effect of adding sunflower seed oil to the effectiveness of a combination of oxybenzone and octyl methoxycinnamate sunscreen, determine the SPF (Sun Protection Factor) value, and determine the pH value of each cream preparation.The research includes the preparation of sunflower seed oil cream (Helianthus annuus), which consists of an in vitro test for SPF value, and  pH test using a spectrophotometer UV-Vis. The results of the average SPF value of  F1 (blank) is 8.24; F2 (blank + Oxybenzone 2% + Octyl methoxycinnamate 5%) is 21.26; F3 (1% sunflower seed oil) is 26.03; F4 (5% sunflower seed oil) is 26.84; and F5 (10% sunflower seed oil) is 28.88. In conclusion, this study result indicate that the addition of sunflower seed oil in various concentrations gives a significant difference in the increase of SPF values ​​between each formula combined with oxybenzone and octyl methoxycinnamate.

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Published
2019-10-10
Section
Articles