Comparison of Anti-Aging Effectiveness from Gotu Kola Extract Cream (Centella asiatica) and Robusta Coffee Cream (Coffea canephora) Toward Hydration Levels in Male Mus Musculus Skin

  • Eka Putri Master of Biomedical Science, Faculty of Medicine, Prima Indonesia University, Medan, North Sumatera, Indonesia
  • Celvin Angkasa Master of Biomedical Science, Faculty of Medicine, Prima Indonesia University, Medan, North Sumatera, Indonesia
  • Chrismis Novalinda Ginting Faculty of Medicine, University of Prima Indonesia, Medan, Sumatera Utara, Indonesia
  • Linda Chiuman Faculty of Medicine, University of Prima Indonesia, Medan, Sumatera Utara, Indonesia
  • I Nyoman Ehrich Lister Department of Physiology, Faculty of Medicine, Prima Indonesia University, Medan, North Sumatera, Indonesia
Keywords: Centella asiatica, Robusta coffee, anti-aging, hydration


Gotu Kola (Centella Asiatica) and Robusta coffee (Coffea Canephora) are natural ingredients that are easily found in the Indonesia environment and contain various types of antioxidants that can provide anti-aging effects or prevent premature aging so that the potential is large enough for development in the science of dermatocosmetology. The aim of this research is to compare the effectiveness of anti-aging extracts of gotu kola herb and robusta coffee toward the levels of hydration in the skin of male white mice. The research data that were processed showed that the data were abnormally distributed (p <0.05). The highest percentage increase in skin hydration level was found in the 10% Robusta coffee treatment group followed by 10% gotu kola herb extract and control. The mean percentage increase in skin hydration levels in all treatment groups was 43.6% with a standard deviation of 27.3. The percentage difference of hydration levels in skin among these groups was significant (p <0.005).


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