Relationship of Body Mass Index (BMI) and Insulin Resistance on Patients Diabetes Mellitus Type-2 in Lampung

  • Evi Kurniawaty Doctoral Program in S3, Biomedicine, Faculty of Medicine, Andalas University, Padang, Indonesia
  • Sumaryati Syukur Departement of Chemistry Faculty of Mathematics and Natural Sciences, Andalas University, Padang, Indonesia
  • Yanwirasti Yanwirasti Departement of Anatomy Faculty of medicine, Andalas University Padang, Indonesia
  • Eti Yerizel Departement of Biochemistry, Faculty of medicine, Andalas University, Padang, Indonesia
Keywords: Body Mass Index, Diabetes Mellitus Type-2, Insulin Resistance.


Diabetes Melitus (DM) Type-2 is a disease that arises in a person caused by high blood sugar levels due to disorders of secretion, insulin work or both. Diabetes Melitus Type-2 is more common than other types. According to Body Mass Index (BMI) is the main risk factor for the occurrence of DM type-2. Excess weight can make cells not sensitive to insulin (insulin resistant). Insulin plays a role in increasing glucose uptake in many cells and also regulates carbohydrate metabolism, so that if insulin resistance occurs, the sugar levels in the blood can experience interference. The purpose of this study was to determine the relationship of body mass index and insulin resistance in patients with DM type-2. The research method used was analytic observation with a cross sectional approach. The research subjects were 44 patients with DM type-2 and 44 non-DM patients. The instruments used were microtoise and weight scales to measure body mass index, insulin examination using the ELISA method to measure insulin resistance (HOMA IR) and then performed statistical tests using Chi-Square analysis. The results of statistical tests on insulin resistance p = 0.028, with α = 5%, there was significant relationship between HOMA IR in patients DM type-2 with the control group. The results of the BMI statistical test obtained p = 0.000, α = 5%, so there was a significant relationship between BMI in patients DM type-2 with the control group. Based on the results of the study it can be concluded that insulin resistance and body mass index have a significant relationship with patients DM type-2.


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