Evaluation of a Constructed Optical Coherence Tomography System

  • Sohad Elwakeel Institute of Laser, Sudan University of Science and Technology, P.O.Box:407, Khartoum, Sudan
  • Nafie ALmuslet Institute of Laser, Sudan University of Science and Technology, P.O.Box:407, Khartoum, Sudan
  • Yahia Badr a ldien cNational Institute of Laser Enhanced Science, Cairo University, Egypt
  • Khalid Haroun Facility of Radiobiological and Imagine Science, Alzaaim Alazahari University, Khartoum, Sudan
Keywords: Tomography Imaging, FT, Optical properties (, ).


The objective of this work is to design and construct an optical coherence tomography (OCT) system, beside the comparison of the efficiency of this system with other tomography systems, like Photoacoustic system, to evaluate its operation. Michelson interferometer was designed; which represent the heart of the system. Two types of laser sources were used; they were He-Ne laser with wavelength of 632.8 nm and semiconductor laser with wavelengths of (700) nm. Performance of the constructed system was completed by receiving the interference fringes by an optical detector, which was connected to the display unit. Digital oscilloscope, with Fourier transformation, was used to display the signal information in frequency domain. Also CCD camera was used to give two & three dimensional images for the studied samples. The constructed system can be used for many purposes, for examples: measurement of the thickness and determination of the optical properties for different samples. The samples studied by the constructed OCT system were: glass slides, polymer\ pyrex\ carbon coating, layers of onion. To prove the good performance of the constructed OCT system the results were compared with other results gained by a Photoacoustic system for the polymer sample. The comparison proved that the constructed OCT system is operated efficiently and correctly.


. Marc Boone,1,* Mariano Suppa,1 Makiko Miyamoto,1 Alice Marneffe,1 Gregor Jemec,2 and Veronique Del Marmol1, “In vivo assessment of optical properties of basal cell carcinoma and differentiation of BCC subtypes by high-definition optical coherence tomography”, Biomed Opt Express, 7(6), pp 2269–2284, 2016 Jun 1.

. Christoph K. Hitzenberger, Manfred Kullhavy, Franz Lexer, Angela Baumgartner, and Adolf F.Fercher, “In vivo intraocular ranging by wavelength tuning interferometery”, San Jose, California, SPIE Vol.3251, (1998)

. Mehreen Adhi and Jay S. Duker, “Optical coherence tomography – current and future applications”, US, National Library of Medicine National Institutes of Health 2013

. David Turbert, “What Is Optical Coherence Tomography?”, American Academy of Ophthalmology, ( 2018 )

. J. B. Thomsen, B. Sander, M. Mogensen, L. Thrane, T. M. Jørgensen,G. B. E. Jemec, P. E. Andersen , Optical Coherence Tomography: Technique and Applications, springer-Verlag Berlin Heidelberg 2009

. A.F. Fercher and C.K. Hizenberger “Optical Coherence Tomography in Medicine”, Berlin, optical science VoL-l4 Springer, (1999)

. A.F. Fercher, W Drexler, C.K.Hizenberger and T Laser “optical principle and application”, Electronic Journals (2003)

. Lihong V.Wang and Qimin Shen, “Sonoluminescence Tomography of Turbid Media”, San Jose,California, SPIE Vol.359, (1999)

. E.wolf, “On the fundamental theorem of diffraction tomography”, SPIE, San Jose, California (1993)

. Markus Laubscher, Mathieu Ducros, Boris Karamata, Theo Lasser and Rene Salathe, “Vidio rate three dimensional optical coherence tomography”, Optics Vol 1, OSA (2002)

. Tony Ko, Ingmar Hartl, Wolfgang Drexler, Ravi Ghanta, James Fujimoto, “Ultrahigh resolution optical coherence tomography for quantitative topographic mapping of retinal and intraretinal architectural morphology”, SPIE 4619, San Jose, California (2002)

. Hrynchak P1, Simpson T, Optical coherence tomography: an introduction to the technique and its use, Optom Vis Sci. 2000 Jul;77(7):347-56.

. Kaname Uno, Tomoyuki Koike, and Tooru Shimosegawa , Recent development of optical coherence tomography for preoperative diagnosis of esophageal malignancies Biomed Opt Express v.7(6),US National Library of MedicinmNational Institutes of Health 2016

. Adolf F. Fercher, “Optical Coherence Tomography”, journal of biomedical opticas Vol 1 (1996) Maciej Wojtkowski, Raniner leitgeb, Andrzej Kowalczyk, Adolf Fercher, “Fourier domain OCT imaging of human eye in vivo”, SPIE 4619, San Jose, California (2002)

. Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography. Science. 1991;254:1178–1181

. Sull AC, Vuong LN, Price LL, et al. Comparison of spectral/Fourier domain optical coherence tomography instruments for assessment of normal macular thickness. Retina. 2010

. Cheryl D. DiCarlo, W.P. Roach, Donald A. Gagliano, Stephen A. Boppart, Daniel X. Hammer, Ann B. gox and Jameg G. fujimoto, “Coparison of optical coherence tomography imaging of cataracts with histopathology”, journal of biomedical optics Vol 4 (1999)

. James G. Fujimoto, “Optical coherence tomography”, applied Physics, Paris,1v,pp1099-1111, November 2001.

. Jian yu lu, Jiqi Cheng, and Brent D. Cameron, “Low sidelobe limited diffraction optical coherence tomography”, SPIE 4625, San Jose, California (2002)

. Paul Dean, Mark R. Dickinson, Dave P. West, “Optical coherence tomography using a photorefractive polymer composite”, SPIE 4956, San Jose, California (2003)

. D.huang, E.A. Swanson, C.P.Lin, J.S. Schuman, W.G. Stinson, W. chang, m.R. Heee, T.Flotte, k.Gregory, C.A. pulifito, and J.G. Fujimoto, “Optical Coherence Tomography”, Science 254 (1999)

. R.Leitgeba, M.Wojtkowskib, C.K.Hizenbergera, A.F.Ferchera, M.Stickera u, A.Kowalezykb, “depth resolved spectroscopy by frequency domain optical coherence tomography, SPIS, vol.4160, pp.57-61, 2000.

. Christoph K. Hitzenberger,”optical measurement of the axial eye length by laser Doppler interferometery”, investigative ophthalmology & visual science, vol. 32, No. 3, March 1991

. Y.A.Badr1, M.E.Gadallah2. M.F.Hassan3, Y.H.SlSharkawy4, laser induced photoacoustic imaging for characterizing tissue equivalent phantoms, presented at the 2nd Cairo international biomedical engineering conference, 2004.