Comparative Efficacy of Acacia Honey and Aloe Vera Gel on Healing of Induced Lacerated Wound in Rabbits

  • Arsalan Khan Livestock & Dairy Development (Research), Khyber Pakhtunkhwa, Peshawar-25000-Pakistan
  • Khurram Ashfaq Department of Clinical Medicine & Surgery, University of Agriculture, Faisalabad-38040-Pakistan
  • Jalal ud Din Department of Clinical Medicine & Surgery, University of Agriculture, Faisalabad-38040-Pakistan
  • Amjad Ali Livestock & Dairy Development (Research), Khyber Pakhtunkhwa, Peshawar-25000-Pakistan
  • Ambrina Tariq Department of Clinical Medicine & Surgery, University of Agriculture, Faisalabad-38040-Pakistan
  • Sheeraz Ghani Livestock & Dairy Development (Research), Khyber Pakhtunkhwa, Peshawar-25000-Pakistan
  • Najeeb Ullah Livestock & Dairy Development (Extension), Khyber Pakhtunkhwa, Peshawar-25000-Pakistan
  • Yasir Sulaman Department of Clinical Medicine & Surgery, University of Agriculture, Faisalabad-38040-Pakistan
  • Muhammad Farooq Ahmad Department of Clinical Medicine & Surgery, University of Agriculture, Faisalabad-38040-Pakistan
Keywords: Acacia honey, Aloe vera, lacerated wound, tensile strength, wound healing.

Abstract

Wound is an injury as a result of trauma and break in the integrity of skin. For restoration of the continuity of skin, the disrupted skin and anatomical continuity should be managed appropriately for normal and efficient wound healing. Therefore, the study was designed to analyze the comparative efficacy of Acacia honey and Aloe vera gel on lacerated wound induced in rabbits. For this purpose, a total of 18 healthy male rabbits were selected and divided randomly into three groups i.e. Group A, B and C. Lacerated wounds were induced in these rabbits aseptically by sharp blunt scissor, post anesthetization with ketamine hydrochloride @40mg/kg body weight. Rabbits of group A were treated with commercially available Acacia honey applied topically twice daily, group B rabbits were treated with Aloe vera gel topically twice daily while group C served as control and treated with standard treatment pyodine. The efficacy of the treatments was evaluated in terms of wound contraction, wound healing, and tensile strength. Wound contraction was found higher in group A and B compared to group C and increased at day 10. Significant tensile strength was recorded in honey treated group. Healing time of group A and B was lower and statistically significant than the control. 

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Published
2017-07-11
Section
Articles