The Effects of Gender and Age on the Cerebral Ventricles / Brain Ratio Morphometric Study
The evaluation of the normal measurements of the cerebral ventricles in the living human has great importance in the diagnosis and monitoring of several pathologies, some previous studies reported variable results concerning the measurements of ventricles. But, and to best of our knowledge, and what was found in the open literature; there is no enough data concerning normative Sudanese measurement for cerebral ventricles. The aim of the study to analyze the morphometric measurements of the Lateral Ventricles of the brain, in different age group individuals of both genders by MR imaging. descriptive analytical studywere done to show the sizes of brain lateral ventricles on Axial Brain MRI section, in which 80 normal adult Sudanese patients(40 male, 40female), were measured(1.5 Tesla).MR Image were acquired in T1weighted image using axial view of the cerebral hemisphere, the following vertical and longitudinal dimensions of both lateral ventricles, Anterior Horn (A.H), body, Posterior Horn(PH), Brain Width (B.W), Brain Length(B.W), Lateral Ventricle Length( V.L), were measured. Data statistical analyzed were conducted using SPSS (Statistical Presentation System Software) for windows version 14.0 Evaluation, where student test and chi-square test was used for analysis for statistical significance and an ?-level of 0.05were considered with a 95% confidence level and intervals.The results revealed that sex-related difference was detected between genders where the body was found to be larger in male than female, while the age related changes seen in all parts of lateral ventricle when it was increase with increasing age.
This study concluded that regarding sex related difference in Sudanese population our finding reported there is significant statistical difference between genders where the body of lateral ventricle was found to be larger in male than female .Thus, no significant statistical difference between genders concerning the anterior horn and posterior horn. Regarding the age effect on the size of the lateral ventricle, in our study in Sudanese population, the size of the right and left anterior horn of lateral ventricle was increasing with age, this fact also true concern the posterior horn in both sides.Regard ventricular / brain ratio, we found that in our results there is unexplainable decrease in the ratio in group C (36-48 years), and increase in group E (62 – 74 years) (due to brain atrophy).In other hand this ratio remains equal in both genders, and in two sides.
[4,5,6,8] Lectures of Human Anatomy Neuroanatomy Ventricular System and CSF By DR. Abdel-MonemAwadHegazy MB, BCh with honor 1983, Diploma.
 Enlargement of the lateral ventricles has been observed in alcoholism, normal aging, depression, dementia, and schizophrenia (Carlen et al. 1978; Luchins et al. 1979; Weinberger et al. 1979, 1982; Andreasen et al. 1982; Frangos and Athanassenas 1982; Jernigan et al. 1982a, b; Schulz et al. 1983; Luchins et al. 1984; Scott et al. 1984; Targum et al. 1984).
 Gender differences in lateral ventricle measurement (Barron et al. 1976; Haug 1977; Gyldensted 1977; Earnest et al. 1979; Zatz et al. 1982). https://www.books.google.com/books.
 In cross-sectional studies of healthy aging, lateral ventricle size increases (Earnest, Heaton, Wilkinson, &Manke, 1979; Gyldensted, 1977; Hughes &Gado, 1981; Schwartz et al., 1985; Soininen, Puranen, &Riekkinen, 1982; Zatz, Jernigan, &Ahumada, 1982).
 Measurements of the normal ventricular system and hemispheric Sulci of 100 adults with computed tomography (Hang et al.1977). Neuroradiology. 1977 Dec 31; 14(4):183-92.
 Marjorie Le May'1984 this article appears in the May l June 1984 issue of AJNR and the August 1984 issue of AJR. Received November 19.1982; accepted after revision November 1. 1983.1 Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114. AJNR 5:269-275, May l June 1984
 Galwar J, Bull JWD, Du Boulay GH, Marshall J. Computerized axial tomography: the normal EMI scan. Jour of Neurol, Neurosurgery and Psy 1975;38:935-47.
 Gyldensted, C. and Kosteljanetz, M. (1977) Measurements of the Normal Ventricular System and Hemispheric Sulci of 100 Adult Patients with Computed Tomography. Neuroradiology, 14, 138-192. http://dx.doi.org/10.1007/BF00496982
 Monte SM. Disproportionate atrophy of cerebral matter in chronic alcoholics. Arch Neurol 1988 Sep;45(9):990-2
 Bandiera P, Pirino A, Conti M, Achene A, Montella A. Morphometric analysis of the lateral ventricles in living human. Ital J Anat Embryology 1996 Jul-Sep; 101(3):203-9.
 D’Souza DMC, Natekar PE. Morphometric study of the ventricular system of Brain by Computerised Tomography. J AnatSoc India 2007;56(1):19-24
 Garret WJ, Kossoff G, Warren PS. Cerebral ventricular size in children: a two dimensional ultra sonic study. Radiology 1980 Sep;136(3):711-5.
 Erturk M, Kavalioglu G, Ozer MA, Ozgur T. Morphometry of the anterior third ventricle region as a guide for the transcallosal-interforniceal approach. Neuro Med Chir 2004 Jun;44(6):288-92.
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