Microbiology and Antibiotic Sensitivity Pattern of Diabetic Foot Ulcers Patients

Ary Putra Noor, Puntodewo Puntodewo

Abstract


One of complications in diabetes mellitus which occurs in the foot, due to a combination of peripheral vasculopathy, neuropathy and abnormal foot pressure, followed by immunopathy and infections is diabetic foot ulcer [1,2]. Those are a major medical, social, and economic problem and are the leading cause of hospitalization for patients with diabetes. Severe infections can lead to amputations and increasing the burden both to the patient and the hospital2. This study aims to know the microbiology pattern and the antibiotic sensitivity pattern for diabetic diabetic foot ulcer in Sardjito General Hospital. The data were obtained from Clinical Pathology Laboratory Sardjito Hospital. Subject in this study were diabetic foot ulcer patients whom hospitalized and undergo surgical procedure between January 2013, until January 2015. Foot ulcers samples acquired from wound bed during surgery were analyzed microbiologically to provide information about the bacterial pattern and their antibiotic sensitivity. From 64 patient samples analyzed, 27 different kind of bacteria were obtained. Acinetobacter baumanii was the most frequent bacteria isolated from patient in this study (25%), followed by Enterococcus faecalis (8%) and pseudomonas aeruginosa (8%).  The antibiotic sensitivity test was performed using 31 antibiotics, and the result was tabulated. Infection with multi drug resistant bacteria is common in diabetic foot ulcers and is associated with increased requirement for surgical treatment. This study proved that multidrug resistant bacteria also a complicating factor in Sardjito Hospital. There is a need for continuous surveillance of bacteria involved in diabetic foot infections to help determine the choice of suitable antibiotic selection.


Keywords


Diabetic foot ulcer; Bacterial pattern; Antibiotic sensitivity; Acinetoobacter baumanii.

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References


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