Comparison of Antioxidant and Anti-hyaluronidase Activity of Tomato (Solanum lycopersicum L.) Extract and Lycopene

Djohan Djohan, Kristina Kristina, Alhoi Hendry Henderson, I Nyoman Ehrich Lister, Ermi Girsang, Edy Fachrial


Aging process contributed with poor of lifestyle and photodamage can induced wrinkles formation because of extracellular matrix destruction. To investigate the potential of tomato as antiaging sources particularly as the hyaluronidase inhibitor. This study used H2O2 scavenging activity for antioxidant assay and hyaluronidase inhibition activity for the antiaging property.  The Solanum lycopersicum L. extract (SLE) has lower antioxidant activity (221.30 ± 1.94) compared with lycopene (208.37 ± 4.87) through H2O2 scavenging activity. The Solanum lycopersicum L. (119.81 ± 14.23) has lower antiaging activity particularly as anti-hyaluronidase activity compared with lycopene (81.65 ± 5.95). Our findings suggest that the Solanum lycopersicum L. has weak antioxidant activity and moderate antiaging activity, particularly as a hyaluronidase inhibitor. Solanum lycopersicum L. can be used as an antiaging source, particularly as hyaluronidase inhibitor.


Antioxidant; Hyaluronidase; Solanum lycopersicum L.; Lycopene; Antiaging.

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