Antimicrobial Activity of SnO2 Nanoparticles against Escherichia Coli and Staphylococcus Aureus and Conventional Antibiotics

Rexona Khanom, Sahana Parveen, Mahfujul Hasan


The prepared SnO2nanoparticles solution sample was employed for the inactivation of Gram-negative Escherichia coli (ATCC 25922) and Gram-positive Staphylococcus Aureus (ATCC 29213). The antibacterial activity of the synthesized SnO2 nanoparticles was evaluated using zone inhibition method. Antibacterial sensitivity of SnO2 nanoparticles in different dilution and conventional antibiotics were tested. 5 and 10 times of SnO2 nanoparticles solution shows strong inhibitory zone against E-coli and S. Aureus than conventional antibiotics Gentamycin and Nalidixic acid. Nalidixic acid gives no inhibitory zone against E-coli. The results showed that diameters of  inhibited zones of different concentration SnO2 nanoparticles  against Staphylococcus Aureus presented good antibacterial performance than Escherichia coli. As the amount of the nanoparticles in the solution decreases, antibacterial activity decreases.SnO2 nanoparticles show almost equivalent sensitivity  like the  conventional Gentamycin antibiotics and Nalidixic Acid antibiotic shows no resistance in E. Coli. SnO2 nanoparticles show more sensitivity than the  conventional Gentamycin and Nalidixic Acid antibiotics in S. Aureus.


Antimicrobial activity; SnO2 Nanoparticles; Escherichia Coli; Staphylococcus Aureus; Conventional Antibiotics.

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