A Comparative Study of Peel and Seed Extract of Passion Fruit (Passiflora edulis) as Anti Collagenase

Authors

  • Surya Hartanto Master Program of Biomedical Sciences, Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia
  • I Nyoman Ehrich Lister Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia
  • Edy Fachrial Laboratory of Molecular Biology, Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia

Keywords:

Passiflora edulis, antioxidant, anti collagenase, DPPH.

Abstract

Natural plant compound is known to have various effects that are beneficial to human health including as antioxidant and anti-aging. The aim of this study was to investigate the antioxidant activity of passion fruit peel and seeds an the activity in inhibiting collagenase. The ethanolic extract of seed and peel of P.edulis was determined by antioxidant activity using DPPH scavenging method and continued with the investigation of anticollagenase activity. The result showed that the IC50 of peel extract and seed extract of P.edulis were 56.11 ± 2.26 µg/mL and 88.25 ± 14.31 µg/mL respectively. The IC50 of anti-collagenase activity of peel and seed extract of P.edulis were 82.53 ± 1.42 µg/mL and 225.40 ± 9.12 µg/mL respectively. From the result, it concluded that peel and seed extract of P.edulis possesses remarkable potency as anti-collagenase activity and have the potential to be developed as anti-aging skin nutraceutical.

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Published

2019-03-28

How to Cite

Hartanto, S., Ehrich Lister, I. N., & Fachrial, E. (2019). A Comparative Study of Peel and Seed Extract of Passion Fruit (Passiflora edulis) as Anti Collagenase. American Scientific Research Journal for Engineering, Technology, and Sciences, 54(1), 42–48. Retrieved from https://asrjetsjournal.org/index.php/American_Scientific_Journal/article/view/4722

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Vol. 54 No. 1 (2019)

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Articles

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